Hep C Testing Calculator is an interactive tool designed to evaluate the cost-effectiveness of different testing pathways for hepatitis C. The tool uses a mathematical model to simulate HCV disease progression. Users can input custom testing pathways and the cost-effectiveness of each pathway is calculated. This allows users to determine which testing strategies would be appropriate in various localized settings, as hepatitis C prevalence can vary substantially by jurisdiction, and differences in population characteristics and resources create different opportunities for testing and engaging patients in care.
The country can be changed in the tool, which changes the underlying disease burden model. Users can then change the cohort size, HCV prevalence, target screening rate, and treatment cost. An interactive interface allows users to create custom testing pathways, which can include up to 7 different stages: screening, confirmation, liver staging 1, liver staging 2, genotyping, monitoring, and SVR12. The type of test used, cost of the test, testing location (on-site or off-site), and patient follow-up rate for each stage in the screening pathway can be changed. The total costs and outcomes associated with each testing strategy (over a 30-year period) are displayed, and a preferred testing pathway is recommended based on a cost-effectiveness threshold.